HPLC System – Hitachi Chromaster
High-Performance Liquid Chromatography for Advanced Analytical Needs
The Hitachi Chromaster is an advanced High-Performance Liquid Chromatography (HPLC) system designed to deliver reliability, precision, ease of use, and exceptional sensitivity. It is ideal for both routine quality control and demanding research applications across pharmaceutical, environmental, food & beverage, and biotechnology laboratories. The Chromaster series combines Hitachi’s renowned engineering with modern innovations to support a wide range of analytical workflows.
Key Features
-
Maximum operating pressure up to 600 bar (60 MPa)
-
High reproducibility and injection accuracy
-
Ultra-low carry-over thanks to needle-wash optimization
-
State-of-the-art detectors (UV, DAD, RI, Fluorescence, MS) with low noise and drift
-
Touchscreen GUI controller for easy stand-alone operation and system diagnostics
-
Integrated column ovens and degassers for solvent and sample stability
System Modules Overview
🔹 Pumps (5110 / 5160)
Binary gradient pump with dual pistons and pulse compensation system. Flow rate ranges from 0.001 to 9.999 ml/min, with pressure tolerance up to 60 MPa (600 bar). The High Frequency Mode ensures smooth flow and high gradient reproducibility.
🔹 Autosamplers (5260 / 5280)
Available in loop and direct injection configurations. Featuring extremely low carry-over (<0.003%) and temperature control from 1–45°C, ideal for temperature-sensitive compounds. Standard sample capacity: up to 200 vials.
🔹 Column Ovens (5310 / 6310)
Thermostatic chambers that support up to 3 columns of 300 mm (5310) or 6 columns of 100 mm (6310), with Peltier heating ensuring sharp, symmetrical peaks.
🔹 Detectors
-
UV/UV-VIS Detectors (5410 / 5420): Dual-wavelength, high-sensitivity detection with fast response.
-
Diode Array Detector (5430): Wide spectral range (190–900 nm) with 1024-element resolution.
-
Fluorescence Detector (5440): Excellent signal-to-noise ratio (>900) and variable slit.
-
Refractive Index Detector (5450): Ideal for non-UV-absorbing analytes.
-
Mass Spectrometer (5610): Compact ESI detector with a range of m/z 20–1000, designed for fast LC/MS workflows.
🔹 Degasser Unit
6-channel degasser (480 μl/channel) supporting simultaneous solvent degassing for both pump and autosampler.
🔹 Organizer Module
Supports space-saving integration and centralized power supply for all system modules.
🔹 Chromaster Software
Fully integrated control and data analysis software, with support for:
-
Empower®, Chromeleon®, OpenLab®, and Clarity®
-
Wake-up & Sleep scheduling
-
Remote diagnostics and consumable monitoring
Pre-configured Systems Available
Select ready-to-run configurations with:
-
UV, DAD, Fluorescence, MS, or RI detection
-
Loop or Direct Injection
-
Autosampler thermostating
-
Full compliance with GMP/GLP standards
Fields of Application
-
Pharmaceutical product and impurity analysis
-
Food and beverage quality control
-
Environmental pollutant testing
-
Biotech and clinical diagnostics
-
Trace analysis and quantitative research
Technical Specifications – HPLC System Hitachi Chromaster
Module |
Max Pressure (MPa) |
Flow Rate (ml/min) |
Sample Capacity |
Temperature Range (°C) |
Dimensions (mm) |
Weight (kg) |
Power Supply |
Wavelength / RI Range |
Noise / Drift |
Response Time |
|---|---|---|---|---|---|---|---|---|---|---|
| 5110 Pump | 40 (0.001–5), 20 (5–9.999) | 0.001–9.999 | – | – | 340×440×140 | 16 | DC 24V, 4A | – | – | – |
| 5160 Pump | 60 (0.001–2.5), 30 (2.5–5) | 0.001–5.000 | – | – | 340×440×140 | 16 | DC 24V, 4A | – | – | – |
| 5260 Autosampler | 60 | – | 120 × 1.5 ml (standard) | 1–45 | 340×440×280 | 24 | DC 24V, 4A / AC 100–240V | – | – | – |
| 5280 Autosampler | 60 | – | 200 × 1.5 ml (standard) | 1–35 | 340×520×320 | 23 | DC 24V, 4A / AC 100–240V | – | – | – |
| 5310 Column Oven | – | – | – | Ambient–15 to +60 | 410×440×140 | 13 | AC 100–240V | – | – | – |
| 6310 Column Oven | – | – | – | Ambient–15 to +75 | 165×515×689 | 25 | AC 100–240V | – | – | – |
| 5410 UV Detector | – | – | – | Optional 4–30 | 340×440×140 | 14 | DC 24V, 2.5A | 190–600 nm | ≤ 0.5×10⁻⁵ AU / ≤ 1.0×10⁻⁴ AU/h | 0.01–2 |
| 5420 UV-VIS Detector | – | – | – | Optional 4–30 | 340×440×140 | 14 | DC 24V, 2.5A | 190–900 nm | ≤ 0.5×10⁻⁵ AU / ≤ 1.0×10⁻⁴ AU/h | 0.01–2 |
| 5430 DAD Detector | – | – | – | Optional 15–30 | 340×440×140 | 14 | DC 24V, 3.5A | 190–900 nm | ≤ 0.5×10⁻⁵ AU / ≤ 0.4×10⁻³ AU/h | 0.01–2 |
| 5440 Fluorescence Detector | – | – | – | Optional 4–30 | 340×440×280 | 25 | AC 100–240V | Ex: 200–850 nm / Em: 250–900 nm | S/N > 900 (Raman), Variable slit | 0.01–2 |
| 5450 RI Detector | – | – | – | 30–50 | 340×440×140 | 13 | DC 24V, 5A | 1.00 to 1.75 RIU | ≤ 2.5×10⁻⁹ RIU / ≤ 0.2×10⁻⁶ RIU/h | 0.05–6 |
| 5610 MS Detector | – | – | – | – | 440×610×430 | 51 | AC 200–240V | m/z 20–1,000 | – | – |
| Organizer / Power Supply | – | – | – | – | 340×420×200 | 9 | AC 100–240V | – | – | – |
👉 For more information, click here.